iBio (NYSE:IBIO – Get Free Report) and Mateon Therapeutics (OTCMKTS:MATN – Get Free Report) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, earnings, dividends, valuation, institutional ownership, profitability and risk.
Valuation & Earnings
This table compares iBio and Mateon Therapeutics”s revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| iBio | $300,000.00 | 353.50 | -$24.91 million | ($1.00) | -3.07 |
| Mateon Therapeutics | N/A | N/A | -$6.64 million | ($0.02) | -2.33 |
Institutional and Insider Ownership
7.9% of iBio shares are owned by institutional investors. Comparatively, 0.1% of Mateon Therapeutics shares are owned by institutional investors. 2.8% of iBio shares are owned by company insiders. Comparatively, 39.2% of Mateon Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.
Analyst Ratings
This is a summary of current ratings for iBio and Mateon Therapeutics, as provided by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| iBio | 0 | 0 | 3 | 0 | 3.00 |
| Mateon Therapeutics | 0 | 0 | 0 | 0 | 0.00 |
iBio currently has a consensus price target of $4.00, indicating a potential upside of 30.29%. Given iBio’s stronger consensus rating and higher probable upside, equities research analysts plainly believe iBio is more favorable than Mateon Therapeutics.
Risk & Volatility
iBio has a beta of 1.26, suggesting that its stock price is 26% more volatile than the S&P 500. Comparatively, Mateon Therapeutics has a beta of 1.33, suggesting that its stock price is 33% more volatile than the S&P 500.
Profitability
This table compares iBio and Mateon Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| iBio | N/A | -73.15% | -45.51% |
| Mateon Therapeutics | N/A | -64.66% | -42.92% |
Summary
Mateon Therapeutics beats iBio on 7 of the 12 factors compared between the two stocks.
About iBio
iBio, Inc., a biotechnology company, engages in the development of precision antibodies in the United States. It offers IBIO-100, a preclinical anti-fibrotic program for the treatment of systemic scleroderma and idiopathic pulmonary fibrosis; and EngageTx platform, which provides an optimized CD3 T-cell engager antibody panel. The company is also developing vaccine candidates, including IBIO-101, an antibody to reduce tumor growth; Endostatin E4 peptide for use in chemotherapy and immunotherapy; Trop-2 for the treatment Trop-2 positive cancers; MUC16, a tumor-associated epitope; anti-EGFRvIII antibody to treat glioblastoma and other cancers; CCR8 protein candidate for treatment of various cancers; PD-1 agonist for the treatment of rheumatoid arthritis and other inflammatory diseases; and IBIO-400 for the treatment of classical swine fever. iBio, Inc. has agreement with The Texas A&M University System for designing and manufacturing of plant-made biopharmaceuticals; and a research collaboration with the National Institute of Allergy and Infectious Diseases to investigate the potential of the company's AI-driven epitope steering platform for the development of a vaccine for Lassa fever. The company was incorporated in 2008 and is headquartered in Bryan, Texas.
About Mateon Therapeutics
Mateon Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in developing drugs for the treatment of orphan oncology indications. The company's lead product candidate is OT-101, an antisense against TGF-beta, which is in phase 3 clinical trials for pancreatic cancer and glioblastoma, as well as develops OT-101 for the treatment of various viruses, including severe acute respiratory syndrome and coronavirus. It also develops OXi4503 for the treatment of acute myeloid leukemia and myelodysplastic syndromes; and CA4P for the treatment of advanced metastatic melanoma. The company is headquartered in Agoura Hills, California.
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