Upstream Bio, Inc. (NASDAQ:UPB – Get Free Report)’s stock price shot up 6.9% during trading on Tuesday . The stock traded as high as $28.83 and last traded at $29.08. 559,688 shares changed hands during trading, an increase of 42% from the average session volume of 394,945 shares. The stock had previously closed at $27.20.
Wall Street Analysts Forecast Growth
A number of equities research analysts recently weighed in on the stock. Evercore ISI assumed coverage on shares of Upstream Bio in a research note on Tuesday, November 18th. They set an “outperform” rating and a $40.00 price target for the company. Truist Financial assumed coverage on Upstream Bio in a research note on Tuesday, October 14th. They set a “buy” rating and a $47.00 price objective for the company. Lifesci Capital assumed coverage on Upstream Bio in a report on Tuesday, December 2nd. They set an “outperform” rating and a $43.00 target price on the stock. Finally, Weiss Ratings restated a “sell (d-)” rating on shares of Upstream Bio in a research report on Wednesday, October 8th. Three equities research analysts have rated the stock with a Buy rating and one has issued a Sell rating to the stock. Based on data from MarketBeat, the stock currently has an average rating of “Moderate Buy” and a consensus price target of $43.33.
Upstream Bio Stock Up 6.1%
Upstream Bio (NASDAQ:UPB – Get Free Report) last released its earnings results on Wednesday, November 5th. The company reported ($0.63) earnings per share (EPS) for the quarter, topping analysts’ consensus estimates of ($0.78) by $0.15. The firm had revenue of $0.68 million during the quarter, compared to analysts’ expectations of $0.65 million. Upstream Bio had a negative return on equity of 28.71% and a negative net margin of 4,366.77%. On average, equities research analysts predict that Upstream Bio, Inc. will post -4.3 earnings per share for the current fiscal year.
Institutional Trading of Upstream Bio
Institutional investors have recently made changes to their positions in the business. Nuveen LLC acquired a new position in Upstream Bio during the first quarter worth $138,000. Velan Capital Investment Management LP bought a new stake in Upstream Bio during the first quarter worth $655,000. ADAR1 Capital Management LLC acquired a new stake in Upstream Bio in the first quarter valued at $92,000. AQR Capital Management LLC acquired a new stake in Upstream Bio in the 1st quarter valued at about $115,000. Finally, Parkman Healthcare Partners LLC acquired a new stake in Upstream Bio in the 1st quarter valued at about $1,429,000.
Upstream Bio Company Profile
Upstream Bio, Inc, a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease.
Further Reading
- Five stocks we like better than Upstream Bio
- CD Calculator: Certificate of Deposit Calculator
- 3 Insider Moves You Shouldn’t Ignore Heading Into 2026
- Asset Allocation Strategies in Volatile Markets
- 3 AI Names With Big Buybacks: GEV, PSTG, and LSCC Signal Confidence
- Why Invest in 5G? How to Invest in 5G Stocks
- Western Digital’s Nasdaq-100 Entry Caps Its AI-Driven Comeback
Receive News & Ratings for Upstream Bio Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Upstream Bio and related companies with MarketBeat.com's FREE daily email newsletter.
