Arvinas (NASDAQ:ARVN – Get Free Report) and Valneva (NASDAQ:VALN – Get Free Report) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their valuation, dividends, risk, institutional ownership, earnings, profitability and analyst recommendations.
Profitability
This table compares Arvinas and Valneva’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Arvinas | 2.94% | 1.91% | 1.29% |
| Valneva | -110.33% | -153.20% | -39.50% |
Analyst Recommendations
This is a breakdown of current recommendations for Arvinas and Valneva, as reported by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Arvinas | 1 | 2 | 5 | 1 | 2.67 |
| Valneva | 2 | 0 | 1 | 0 | 1.67 |
Arvinas currently has a consensus price target of $15.40, suggesting a potential upside of 102.76%. Valneva has a consensus price target of $9.30, suggesting a potential upside of 65.78%. Given Arvinas’ stronger consensus rating and higher probable upside, analysts plainly believe Arvinas is more favorable than Valneva.
Institutional & Insider Ownership
95.2% of Arvinas shares are held by institutional investors. Comparatively, 11.4% of Valneva shares are held by institutional investors. 7.3% of Arvinas shares are held by company insiders. Comparatively, 14.9% of Valneva shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.
Valuation & Earnings
This table compares Arvinas and Valneva”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Arvinas | $316.70 million | 1.55 | -$80.80 million | $0.10 | 75.95 |
| Valneva | $197.56 million | 2.69 | -$130.33 million | ($2.11) | -2.66 |
Arvinas has higher revenue and earnings than Valneva. Valneva is trading at a lower price-to-earnings ratio than Arvinas, indicating that it is currently the more affordable of the two stocks.
Risk and Volatility
Arvinas has a beta of 1.8, indicating that its stock price is 80% more volatile than the S&P 500. Comparatively, Valneva has a beta of 1.53, indicating that its stock price is 53% more volatile than the S&P 500.
Summary
Arvinas beats Valneva on 13 of the 15 factors compared between the two stocks.
About Arvinas
Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. The company engineers proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body’s own natural protein disposal system to degrade and remove disease-causing proteins. Its product pipeline includes Bavdegalutamide and ARV-766, investigational orally bioavailable PROTAC protein degraders for the treatment of men with metastatic castration-resistant prostate cancer, which are in Phase 1/2 clinical trials; and ARV-471, an orally bioavailable estrogen receptor degrading PROTAC targeted protein degrader for the treatment of patients with locally advanced or metastatic estrogen receptor+/human epidermal growth factor receptor 2-breast cancer, which is Phase 3 clinical trial. Arvinas, Inc. has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., Carrick Therapeutics Limited, and Bayer AG. The company was founded in 2013 and is based in New Haven, Connecticut.
About Valneva
Valneva SE, a specialty vaccine company, develops, manufactures, and commercializes prophylactic vaccines for infectious diseases with unmet needs. It offers IXIARO, an inactivated Vero cell culture-derived Japanese encephalitis vaccine indicated for active immunization against Japanese encephalitis; DUKORAL, an oral vaccine for the prevention of diarrhea caused by Vibrio cholera and/or heat-labile toxin producing enterotoxigenic Escherichia coli bacterium; IXCHIQ, a single-dose, live-attenuated vaccine for the prevention of disease caused by chikungunya virus; and VLA2001, an inactivated whole-virus COVID-19 vaccine. The company also develops VLA15, a vaccine candidate, which is in Phase III clinical trial against Borrelia, the bacterium that causes Lyme disease; VLA1553, a vaccine candidate, which is in Phase III clinical trial against the chikungunya virus; VLA1554, a vaccine candidate targeting human metapneumovirus; and VLA2112, a vaccine candidate to treat patients with epstein-barr virus. It sells its products in the United States, Canada, Germany, Austria, Nordics, the United Kingdom, France, rest of European countries, and internationally. Valneva SE has collaborations with Pfizer, Inc. to co-develop and commercialize its Lyme disease vaccine; and Instituto Butantan for the development, manufacturing, and marketing of single-shot chikungunya vaccine. The company was founded in 1998 and is based in Saint-Herblain, France.
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