Head-To-Head Review: Prime Medicine (NYSE:PRME) versus ZIVO Bioscience (NASDAQ:ZIVO)

Prime Medicine (NYSE:PRME) and ZIVO Bioscience (NASDAQ:ZIVO) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, risk, institutional ownership, profitability, analyst recommendations, valuation and dividends.

Profitability

This table compares Prime Medicine and ZIVO Bioscience’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
Prime Medicine	N/A	-107.87%	-74.97%
ZIVO Bioscience	N/A	N/A	-2,240.92%

Institutional and Insider Ownership

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 12.8% of ZIVO Bioscience shares are owned by institutional investors. 22.7% of Prime Medicine shares are owned by insiders. Comparatively, 48.9% of ZIVO Bioscience shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Earnings & Valuation

This table compares Prime Medicine and ZIVO Bioscience”s top-line revenue, earnings per share and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Prime Medicine	$5.98 million	107.82	-$198.13 million	($1.44)	-2.48
ZIVO Bioscience	$15,850.00	2,572.52	-$7.78 million	($2.18)	-4.70

ZIVO Bioscience has lower revenue, but higher earnings than Prime Medicine. ZIVO Bioscience is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a summary of current ratings and recommmendations for Prime Medicine and ZIVO Bioscience, as reported by MarketBeat.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Prime Medicine	0	3	4	0	2.57
ZIVO Bioscience	0	0	0	0	0.00

Prime Medicine currently has a consensus price target of $7.21, indicating a potential upside of 101.91%. Given Prime Medicine’s stronger consensus rating and higher possible upside, equities analysts plainly believe Prime Medicine is more favorable than ZIVO Bioscience.

Volatility & Risk

Prime Medicine has a beta of 2.7, suggesting that its share price is 170% more volatile than the S&P 500. Comparatively, ZIVO Bioscience has a beta of 0.19, suggesting that its share price is 81% less volatile than the S&P 500.

Summary

Prime Medicine beats ZIVO Bioscience on 9 of the 13 factors compared between the two stocks.

About Prime Medicine

Prime Medicine, Inc., a biotechnology company, delivers genetic therapies to address the spectrum of diseases by deploying gene editing technology. The company offers Prime Editors with a Prime Editor protein, comprising a fusion between a Cas protein and a reverse transcriptase enzyme; and a pegRNA, which targets the Prime Editor to a specific genomic location and provides a template for making the desired edit to the target DNA sequence. It has a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded-Cell & Immunotherapy Pairs for genetic diseases, acute myeloid leukemia, and myelodysplastic syndrome. The company was incorporated in 2019 and is based in Cambridge, Massachusetts.

About ZIVO Bioscience

ZIVO Bioscience, Inc., a research and development company, engages in licensing and selling natural bioactive ingredients derived from its proprietary algae cultures to animal, human, and dietary supplement and medical food manufacturers. The company operates in the biotech and agtech sectors, with an intellectual property portfolio comprising proprietary algal and bacterial strains, biologically active molecules and complexes, production techniques, cultivation techniques, and patented or patent-pending inventions for applications in human and animal health. Its products indications include poultry gut health, bovine mastitis, canine joint health, human immune modification, algal biomass for human consumption, and biomass for supporting skin health / anti-aging. The company was formerly known as Health Enhancement Products, Inc. and changed its name to ZIVO Bioscience, Inc. in October 2014. ZIVO Bioscience, Inc. is headquartered in Bloomfield Hills, Michigan.