Contrasting BioCardia (BCDA) & Twist Bioscience (TWST)

BioCardia (OTCMKTS:BCDA) and Twist Bioscience (NASDAQ:TWST) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their analyst recommendations, valuation, earnings, dividends, institutional ownership, risk and profitability.

Analyst Recommendations

This is a breakdown of recent ratings for BioCardia and Twist Bioscience, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCardia 0 0 0 0 N/A
Twist Bioscience 0 1 2 0 2.67

Twist Bioscience has a consensus target price of $25.99, indicating a potential upside of 0.00%. Given Twist Bioscience’s higher possible upside, analysts clearly believe Twist Bioscience is more favorable than BioCardia.

Valuation and Earnings

This table compares BioCardia and Twist Bioscience’s revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
BioCardia $630,000.00 69.26 -$13.99 million N/A N/A
Twist Bioscience $25.43 million 28.66 -$71.23 million ($25.51) -1.02

BioCardia has higher earnings, but lower revenue than Twist Bioscience.


This table compares BioCardia and Twist Bioscience’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
BioCardia -2,191.28% -423.10% -227.05%
Twist Bioscience N/A N/A N/A

Insider & Institutional Ownership

0.1% of BioCardia shares are owned by institutional investors. Comparatively, 22.3% of Twist Bioscience shares are owned by institutional investors. 26.0% of BioCardia shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.


Twist Bioscience beats BioCardia on 7 of the 10 factors compared between the two stocks.

BioCardia Company Profile

BioCardia, Inc., a clinical-stage regenerative medicine company, develops therapeutics for cardiovascular diseases. Its lead therapeutic candidate is the CardiAMP Cell Therapy System for the treatment of heart failure and chronic myocardial ischemia. The company is also developing CardiALLO Cell Therapy System, an investigational culture expanded bone marrow derived from mesenchymal cell therapy, which is in Phase I/II trial for the treatment of ischemic systolic heart failure. In addition, it offers the Helix biotherapeutic delivery system; and Morph vascular access product line, which provides catheter products. BioCardia, Inc. is based in San Carlos, California.

Twist Bioscience Company Profile

Twist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools for sample preparation, antibody libraries for drug discovery and development, and DNA as a digital data storage medium. Twist Bioscience Corporation has a collaboration agreement with Pandion Therapeutics, Inc. to apply its antibody optimization platform for a targeting arm of a bispecific antibody. The company was founded in 2013 and is headquartered in San Francisco, California.

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