Reviewing Akari Therapeutics (AKTX) and Clementia Pharmaceuticals (CMTA)

Akari Therapeutics (NASDAQ: AKTX) and Clementia Pharmaceuticals (NASDAQ:CMTA) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their profitability, institutional ownership, risk, valuation, dividends, earnings and analyst recommendations.

Earnings and Valuation

This table compares Akari Therapeutics and Clementia Pharmaceuticals’ revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Akari Therapeutics N/A N/A -$18.14 million ($0.28) -7.61
Clementia Pharmaceuticals N/A N/A -$115.45 million N/A N/A


This table compares Akari Therapeutics and Clementia Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Akari Therapeutics N/A -152.12% -102.69%
Clementia Pharmaceuticals N/A N/A -117.13%

Institutional & Insider Ownership

32.9% of Akari Therapeutics shares are owned by institutional investors. Comparatively, 68.0% of Clementia Pharmaceuticals shares are owned by institutional investors. 61.8% of Akari Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Analyst Recommendations

This is a summary of current recommendations and price targets for Akari Therapeutics and Clementia Pharmaceuticals, as provided by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akari Therapeutics 0 2 2 0 2.50
Clementia Pharmaceuticals 0 0 4 0 3.00

Akari Therapeutics presently has a consensus price target of $6.83, indicating a potential upside of 220.81%. Clementia Pharmaceuticals has a consensus price target of $27.00, indicating a potential upside of 48.11%. Given Akari Therapeutics’ higher probable upside, equities research analysts clearly believe Akari Therapeutics is more favorable than Clementia Pharmaceuticals.

About Akari Therapeutics

Akari Therapeutics, Plc, formerly Celsus Therapeutics Plc, is a clinical-stage biopharmaceutical company. It is focused on the development and commercialization of treatments for a range of rare and orphan autoimmune and inflammatory diseases caused by dysregulation of complement component 5 (C5), including paroxysmal nocturnal hemoglobinuria, Guillain Barre syndrome and atypical Hemolytic Uremic Syndrome. Its lead drug, Coversin, a complement inhibitor, acts on complement C5, preventing release of C5a and formation of C5b-9. Coversin is a recombinant small protein derived from a protein discovered in the saliva of the Ornithodoros moubata tick, where it modulates the host immune system to allow the parasite to feed without alerting the host to its presence or provoking an immune response. It is conducting Phase Ib clinical trial of Coversin. It focuses on rare and orphan diseases, including disease states spanning hematology, nephrology, transplantation, neurology and ophthalmology.

About Clementia Pharmaceuticals

Clementia Pharmaceuticals Inc. is a clinical stage biopharmaceutical company. The Company is engaged in developing disease-modifying treatments for patients suffering from debilitating bone and other diseases with high unmet medical need. Its lead product candidate, palovarotene, is an oral small molecule that binds and activates retinoic acid receptor gamma (an RARg agonist), and has activity in preventing abnormal new bone formation as well as scar tissue formation (or fibrosis) in a variety of tissues in animal models. It is developing palovarotene for the treatment of Fibrodysplasia Ossificans Progressiva (FOP) and Multiple Osteochondroma (MO). Its programs focus on diseases involving tissue transformation via retinoic acid receptors (RARs). The Company also has an eye drop formulation of palovarotene that can potently increase tear production and decrease corneal damage.

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