Clovis Oncology (CLVS) and Mersana Therapeutics (MRSN) Head to Head Analysis

Mersana Therapeutics (NASDAQ: MRSN) and Clovis Oncology (NASDAQ:CLVS) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their valuation, analyst recommendations, institutional ownership, profitability, risk, earnings and dividends.

Insider & Institutional Ownership

76.7% of Mersana Therapeutics shares are held by institutional investors. 12.5% of Clovis Oncology shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.


This table compares Mersana Therapeutics and Clovis Oncology’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Mersana Therapeutics N/A N/A N/A
Clovis Oncology -947.47% -122.06% -38.84%

Earnings & Valuation

This table compares Mersana Therapeutics and Clovis Oncology’s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Mersana Therapeutics N/A N/A N/A N/A N/A
Clovis Oncology $80,000.00 36,151.00 -$349.13 million ($8.28) -7.13

Mersana Therapeutics has higher earnings, but lower revenue than Clovis Oncology.

Analyst Ratings

This is a summary of current ratings and price targets for Mersana Therapeutics and Clovis Oncology, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mersana Therapeutics 0 0 4 0 3.00
Clovis Oncology 0 6 11 0 2.65

Mersana Therapeutics currently has a consensus target price of $23.67, suggesting a potential upside of 53.28%. Clovis Oncology has a consensus target price of $91.92, suggesting a potential upside of 55.78%. Given Clovis Oncology’s higher possible upside, analysts plainly believe Clovis Oncology is more favorable than Mersana Therapeutics.


Mersana Therapeutics beats Clovis Oncology on 5 of the 9 factors compared between the two stocks.

About Mersana Therapeutics

Mersana Therapeutics, Inc. is a United States-based biotechnology company focused on discovering and developing a pipeline of antibody drug conjugates (ADCs). The Company focuses on advancing a pipeline of targeted oncology therapeutics leveraging its Fleximer immunoconjugate technology. The Fleximer platform allows it to design ADCs with specific properties and manage the drug’s chances of attacking cancers. Its product candidates include XMT-1522 and XMT-1536. The ADC therapies treat cancer patients by engineering a drug conjugate with various anti-cancer agents and controlling when, where and how those agents are released. Dolaflexin is its Fleximer antibody drug conjugation platform, which pairs the Fleximer polymer with its linker chemistries to create ADC therapies. XMT-1522 is based on its Dolaflexin platform and has over 15 auristatin molecules per antibody. XMT-1522 is in Phase I clinical trial for various indications of cancers. XMT-1536 is in pre-clinical development.

About Clovis Oncology

Clovis Oncology, Inc. is a biopharmaceutical company focused on acquiring, developing and commercializing anti-cancer agents in the United States, Europe and other international markets. The Company’s product candidates include Rociletinib, Rubraca (Rucaparib) and Lucitanib. Rucaparib is an oral, small molecule poly adenosine diphosphate (ADP)-ribose polymerase (PARP) inhibitor of PARP1, PARP2 and PARP3 approved as a monotherapy for the treatment of patients with deleterious breast cancer (BRCA) (human genes associated with the repair of damaged deoxyribonucleic acid (DNA)) mutation (germline and/or somatic) associated advanced ovarian cancer. Lucitanib is an oral inhibitor of the tyrosine kinase activity of vascular endothelial growth factor receptors (VEGFR) 1-3, platelet-derived growth factor receptors (PDGFR) alpha and beta and fibroblast growth factor receptors (FGFR) 1-3. Rociletinib is an oral mutant-selective inhibitor of epidermal growth factor receptor (EGFR).

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